Introduction to Creatinine Clearance

The Creatinine function provides the ability to calculate Creatinine Clearances used to determine Amantadine dosage required for patients. This is especially useful for flu breakouts.

The Creatinine function is available from both the Patient folder and the Groups folder. Accessing this function from the Groups folder allows you to calculate Amantidine dosages for all patients in the group, while the same function in the Patient folder allows the dosage to be determined for a single patient.

The formula used to calculate Creatinine Clearance differs for males and females. The user must have a value for Serum Creatinine in order to perform the calculations. The patient’s age and weight are also required. Once this information is provided, PharmaClik Rx can calculate the Creatinine Clearance.

The following codes are used in the calculations:

• SrCr = Serum Creatinine
• CrCl = Creatinine Clearance

Creatinine Clearance for Males:

• CrCl (mL/min) = (140 - Age) x Weight SrCl x 0.81
• Creatinine Clearance for Females:
• CrCl (mL/min) = Male CrCl x 0.85

Once the value for Creatinine Clearance is calculated, the user must know if the patient has any form of renal disease in order to determine the appropriate Amantidine dosage. This is required because the existence of renal disease impacts the patient’s Amantidine dosage.

Note: A clearly outlined Amantidine dosage chart is provided by Web Refill. Please note that Amantidine dosage is based on rounded values of Creatinine Clearance.